Waterfront-SEU is an island platformed Washington Metro station in the Southwest Waterfront neighborhood of Washington, D.C., United States. The station was opened on December 28, 1991, and is operated by the Washington Metropolitan Area Transit Authority (WMATA). Providing service for only the Green Line, the station is located at 4th and M Streets.

The "SEU" refers to the nearby Southeastern University (closed as of 2009) and was added to the name in 1997.